une insuffisance de NO serait cause d'hypertension portale
en agissant sur 2 protéines...
article sur l'hypertension portale :
http://www.snfge.asso.fr/02-Connaitre-maladie/0F-foie-et-voie/faq/foie_hypertension-portale.htm
article sur la découverte :
http://www.news-medical.net/?id=13523
extrait :
"Previous studies have shown that, at the cellular level, portal hypertension results from reduced production of needed nitric oxide, which regulates expansion of the blood vessels.
Dr. Rockey's research identified how the nitric oxide production breaks down due to the effects of the protein GRK2. The protein attaches to another protein called AKT, interrupting the creation of nitric oxide. "
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Le doc d'origine de cette publication :
http://www.utsouthwestern.edu/utsw/cda/dept37389/files/245390.html
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